Pesquisa sobre: AUTOPHAGY-RELATED PROTEIN 7 
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Descritor Inglês:   Autophagy-Related Protein 7 
Descritor Espanhol:   proteína 7 relacionada con la autofagia 
Descritor Português:   Proteína 7 Relacionada à Autofagia 
Sinônimos Inglês:   ATG12 Activating Enzyme E1 ATG7
ATG12-Activating Enzyme E1 ATG7
ATG7 Protein
Autophagy Related Protein 7
Ubiquitin Activating Enzyme E1 like Protein
Ubiquitin Like Modifier Activating Enzyme ATG7
Ubiquitin-Activating Enzyme E1-like Protein
Ubiquitin-Like Modifier-Activating Enzyme ATG7  
Categoria:   D12.776.094.399
Definição Inglês:   An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition. 
Nota Histórica Inglês:   2017 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   56559 
Identificador Único:   D000071193 

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